Endocrine Abstracts

Introduction: Glucocorticoids (GCs) play a crucial role in various physiological processes, with adipose tissue (AT) being an important target organ for their metabolic actions. Besides lipolytic action, the mechanistic regulation of GCs in human AT during physiological exposure is still unclear. We integrated transcriptomic and metabolomic data within the AT to identify mechanistic markers of GC action.Methods: In a randomised, cross-over trial, ten pat...